Implications of changing Os level Virtual Memory setting and turning on LargeAddressAware flag?

Question

I am working on a legacy memory intensive dotnet application which reads data from database, process the data in memory and writes the process data to an external file in a single transaction.

Application is 64 bit written in wpf as front end and csharp and sql at back.

At the moment above transaction is executed in a series of programmatic batches depending on data selection by user.

I wanted to understand implications of doing Virtual Memory changes against 8 gb available RAM. Specifically what are the potential issues with these configurations?

Do I need to change the existing algorithm to see any performance benefit?