Implementing breakpoints on variable value changes during step debugging without conditional breakpoint

Question

Is there an effective method to pause execution during step-by-step debugging when a specific variable's value is altered, without the prerequisite of establishing a conditional breakpoint in advance?

Take, for instance, the practice of monitoring variables through the watch functionality while conducting step debugging. Is there a mechanism that automatically stops execution at the exact moment a watched variable's value is modified?

Such a feature would enable a more efficient debugging process, allowing for an immediate transition to the segment of code responsible for the change, thereby eliminating the need for extensive code inspection.

I am particularly interested in identifying the precise line in my code that modifies the value of a custom cookie named IS_APP within the $_COOKIE superglobal amidst a complex framework. Before embarking on an in-depth examination, I am curious to know if such a debugging capability exists.