mysql optimization for a lot of data

Question

I would like your opinions on a db schema I will be creating. The db will hold data from different languages. Daily the inserts will be around 30.000 - 50.000, with heavy reads. I can have just 6 tables holding the data for every language or I can create 6 different tables for each language. Will the second option be more efficient for heavy reads? What other techniques do you suggest, to help the system's performance (data partitioning etc)?

Thanks